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Characterizing Disorder in Pharmaceutical Materials
Insights from DVS and IGC SEA

Pharmaceutical solids rarely exist in a simple, perfectly ordered state. From polymorphs and solvates to defect sites and amorphous regions, subtle variations in thermodynamic stability can profoundly influence formulation performance, processing behavior, and long-term storage stability.

In this technical case study, Surface Measurement Systems explores how Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (IGC SEA) provide powerful, complementary insight into crystalline and disordered materials.

Download the Case Study
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Discover how vapor sorption techniques can:

  • Differentiate polymorphs and hydrates
  • Quantify amorphous content below 1%
  • Monitor glass transition and crystallization
  • Detect processing-induced surface changes

    If solid-state stability matters to your formulation strategy, this paper provides the data and insight to support confident development decisions.

    Screenshot 2025-07-31 at 2.10.16 PM

    Read the Case Study Now!

    Download the full case study to explore the results in detail.

    Download the Case Study

    Characterizing Disorder in Pharmaceutical Materials
    Insights from DVS and IGC SEA

    Pharmaceutical solids rarely exist in a simple, perfectly ordered state. From polymorphs and solvates to defect sites and amorphous regions, subtle variations in thermodynamic stability can profoundly influence formulation performance, processing behavior, and long-term storage stability.

    In this technical case study, Surface Measurement Systems explores how Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (IGC SEA) provide powerful, complementary insight into crystalline and disordered materials.

    Download the Case Study
    Copy of YouTube Banner - Discover the BTA Frontier Today!-9

    Discover how vapor sorption techniques can:

    • Differentiate polymorphs and hydrates
    • Quantify amorphous content below 1%
    • Monitor glass transition and crystallization
    • Detect processing-induced surface changes

      If solid-state stability matters to your formulation strategy, this paper provides the data and insight to support confident development decisions.

      What This Case Study Covers

      Using a promising MOF supplied by novoMOF, the study illustrates how DVS Carbon and BTA Frontier enable detailed assessment of carbon capture materials under mixed-gas conditions.

      Inside the case study, you’ll learn:

      • CO₂ uptake, kinetics, and cycling stability at post-combustion-relevant concentrations

      • The influence of relative humidity on capacity and material stability

      • Insights from co-adsorption experiments combining CO₂ and H₂O

      • Breakthrough analysis quantifying competitive adsorption under mixed-gas flows

      • How integrated DVS and BTA data support faster, more confident material screening

        Why DVS Carbon & BTA Frontier?

        Understanding sorbent performance under humidity is essential but often experimentally complex and time-consuming.

        By integrating high-resolution gravimetric sorption analysis with dynamic breakthrough testing, DVS Carbon and BTA Frontier allow researchers to work with small sample quantities and control humidity and gas composition precisely. They also have the ability to quantify capacity, kinetics, stability, and regeneration behavior with confidence.

        Together, they provide a comprehensive, process-relevant toolkit for evaluating advanced carbon capture materials.

        Screenshot 2025-07-31 at 2.10.16 PM

        Read the Case Study Now!

        Download the full case study to explore the results in detail.

        Download the Case Study

        Characterizing Disorder in Pharmaceutical Materials
        Insights from DVS and IGC SEA

        Pharmaceutical solids rarely exist in a simple, perfectly ordered state. From polymorphs and solvates to defect sites and amorphous regions, subtle variations in thermodynamic stability can profoundly influence formulation performance, processing behavior, and long-term storage stability.

        In this technical case study, Surface Measurement Systems explores how Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (IGC SEA) provide powerful, complementary insight into crystalline and disordered materials.

        Download the Case Study
        Copy of YouTube Banner - Discover the BTA Frontier Today!-9

        Characterizing Disorder in Pharmaceutical Materials
        Insights from DVS and IGC SEA

        Pharmaceutical solids rarely exist in a simple, perfectly ordered state. From polymorphs and solvates to defect sites and amorphous regions, subtle variations in thermodynamic stability can profoundly influence formulation performance, processing behavior, and long-term storage stability.

        In this technical case study, Surface Measurement Systems explores how Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (IGC SEA) provide powerful, complementary insight into crystalline and disordered materials.

        Download the Case Study
        Copy of YouTube Banner - Discover the BTA Frontier Today!-9

        Characterizing Disorder in Pharmaceutical Materials
        Insights from DVS and IGC SEA

        Pharmaceutical solids rarely exist in a simple, perfectly ordered state. From polymorphs and solvates to defect sites and amorphous regions, subtle variations in thermodynamic stability can profoundly influence formulation performance, processing behavior, and long-term storage stability.

        In this technical case study, Surface Measurement Systems explores how Dynamic Vapor Sorption (DVS) and Inverse Gas Chromatography (IGC SEA) provide powerful, complementary insight into crystalline and disordered materials.

        Download the Case Study
        Copy of YouTube Banner - Discover the BTA Frontier Today!-9

        Discover how vapor sorption techniques can:

        • Differentiate polymorphs and hydrates
        • Quantify amorphous content below 1%
        • Monitor glass transition and crystallization
        • Detect processing-induced surface changes

          If solid-state stability matters to your formulation strategy, this paper provides the data and insight to support confident development decisions.

          Why DVS Carbon & BTA Frontier?

          Understanding sorbent performance under humidity is essential but often experimentally complex and time-consuming.

          By integrating high-resolution gravimetric sorption analysis with dynamic breakthrough testing, DVS Carbon and BTA Frontier allow researchers to work with small sample quantities and control humidity and gas composition precisely. They also have the ability to quantify capacity, kinetics, stability, and regeneration behavior with confidence.

          Together, they provide a comprehensive, process-relevant toolkit for evaluating advanced carbon capture materials.

          Screenshot 2025-07-31 at 2.10.16 PM

          Read the Case Study Now!

          Download the full case study to explore the results in detail.

          Download the Case Study

          Test your materials, on us!
          Secure Your Free Sample Analysis Today!

          For a limited time, Surface Measurement Systems is offering select researchers complimentary analysis using our world-class sorption instruments.

          Get precise kinetic and equilibrium data to accelerate your next breakthrough.

          Access This Offer!
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          What Can You Learn from a Free Sample Analysis?

           

          With Dynamic Vapor Sorption (DVS)
          Measure moisture sorption behavior, kinetics, equilibrium times, and stability for single or multicomponent systems, including co-adsorption of gases and vapors (e.g., humid CO₂).

          With Surface Energy Analyzer (SEA)
          Assess surface energy distribution and heterogeneity to evaluate reactivity, affinity, agglomeration, flow, and adhesion properties.

          With Breakthrough Analyzer (BTA)
          Determine sorption capacities, equilibration times, and breakthrough curves for single or multicomponent species during both sorption and desorption to assess regeneration and cycle performance.

          With Membrane Permeation Analyzer (MPA)
          Analyze membrane diffusion and permeability for single or multicomponents, measuring the impact of water, oxygen, and other species on performance.

          What You’ll Walk Away With:

          High-resolution data on sorption behavior

          Evidence and sharable results to support team buy-in and funding approval

          Insights into material performance under real-world conditions

          An opportunity to explore if our instruments are a fit for your lab

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          Who Should Apply?

           

          This offer is ideal for scientists, engineers, and R&D teams who:

          • Are exploring new materials
          • Need proof-of-concept data
          • Are evaluating advanced analytical instrumentation
          • Are preparing for scale-up or publication
            Screenshot-2025-07-31-at-2.08.16-PM1-SZD

            Get in touch with us today!

            Don’t miss out, get your free sample analysis started today. This offer is only good through September 2025. 

            Fill out the form below to apply.

            Limited time offer, and only one submission per organization will be accepted. View the terms and conditions for full details.

            Get Free Sample Analysis!

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