Online Workshop: Liquid and Gas Chromatographic Methods for Studying Solid and Solute Properties and Interactions



Tues 5 April 2022

1:00 pm BST | 2:00 pm CEST | 8:00 am EDT


1-2 hours incl. Q&A
Register free here

Organized in
coordination with:

Presenters:Dr Daryl Williams

Prof. Daryl Williams

Join this in-depth workshop to discover how advanced sorption techniques can be used to gain accurate and reliable data on the interaction between different medias and surface and bulk properties of materials. This will be explored by one of the world’s leading experts in sorption science, Professor of Particle Science at Faculty of Engineering, Department of Chemical Engineering, Imperial College London, and Founder & MD of Surface Measurement Systems, Prof. Daryl Williams.

Though chromatographic methods tend to be associated with analytical chemistry as well as separations science, chromatographic approaches are powerful physical chemistry methods for understanding interactions between solids and solutes, both in the gas and liquid phases.

Organized in coordination with the Collaborative Research Centre 1411 Design of Particulate Products, FAU – Erlangen, This presentation will review a number of the physical chemistry based chromatographic approaches, and will give a number of examples of these methods in operation including:

  • Inverse gas chromatography determination of adsorbent surface areas including freeze dried solids, at room temperature and room humidity[1]
  • Determination of diffusion constants for porous catalysts for liquid phase reactants using zero column length chromatography
  • Protein-protein interactions in solution and aggregation propensity using self interaction chromatography to determine second virial coefficients[2]

With the opportunity to have your questions answered directly by Prof. Williams in a live Q&A, this is a can’t miss session for any conducting characterization research in their work.

Prof. Daryl R. Williams

Prof. Daryl R. Williams graduated with a B.Sc. (Hons) in Physical Chemistry from University of Melbourne, Australia and a M.Sc. in Polymer Science from Lehigh University, USA before coming to Imperial College London complete his PhD. He is Founder and Managing Director of Surface Measurement Systems and the Professor of Particle Science in the Department of Chemical Engineering at Imperial College.

Prof. Williams has published over 100 papers in refereed journals and been granted international 5 patents. His research interests include the surface and bulk characterisation of complex organic solids, including especially biopharmaceuticals, foods, pharmaceuticals and polymers as well as their manufacture using spray drying, crystallisation, freeze drying, milling and granulation. The Surface and Particle Engineering Laboratory at Imperial College he leads has 4 Postdoctoral research fellows and 11 PhD students.

He has invented one and has led the commercialisation of two standard techniques for materials characterisation, the Dynamic Vapour Sorption (DVS) and the Inverse Gas Chromatography (iGC) methods via Surface Measurement Systems. His work has been recognised by Imperial College with the President’s Medal in 2017, the EEF’s Future Manufacturing Award in Innovation for 2018 and the Institution of Chemical Engineers’ Geldart Medal in 2018/19 for his “major contribution to particle technology”.

Register free here

[1] Measuring the specific surface area (SSA) of freeze-dried biologics using inverse gas chromatography, Duralliu A, Matejtschuk P, Williams DR,  European Journal of Pharmaceutics and Biopharmaceutics,: 142, Pages: 216-221, 2019

[2] Mapping the mAb Aggregation Propensity Using Self-Interaction Chromatography as a Screening Tool,  Sarah H.M. Hedberg, DongKyu Lee, Yash Mishra, Jonathan M. Haigh, and Daryl R. Williams,  Analytical Chemistry,  2018, 90, 6, 3878–3885, 2018