Applications

• Water sorption kinetics and isotherms
• Hygroscopicity of pharmaceutical solids
• Tg and RH phase transitions in polymers
• Amorphous content determination of solids
• Diffusion and permeation in polymers
• Food, flavors, and fragrances
• Sorbents
• Wood and cellulosic materials
• Composites
• Hydrophilic and hydrophobic materials.

Schematics

This schematic displays the basic functioning principles of the DVS Discovery instrument.

 

Specifications

Temperature

• Temperature controlled enclosure
• Control range: 10 °C to 70 °C
• Temperature stability ± 0.05 °C over 6 hours
• Temperature resolution 0.01 °C

High-Temperature Pre-heater for drying up to 2 samples

• 200 ^oC (maximum local temperature)
• Heating ramp rates: up to 5 ºC/min
• Temperature sensor: Pt-100

Discovery stand

• Manifold: 316 stainless steel
• Seals: Viton® and Kalrez® or equivalent
• Tubing: 1/4 inch stainless steel

Solvent Reservoir

• 1 glass reservoir as standard
• Optional heated reservoir

Flow control

• High-accuracy digital mass flow controllers
• Wide dynamic range – turndown ratio 1000:1
• Carrier Gas – Dry air or Nitrogen

Relative humidity

• Relative humidity range from 0 to 98% for 10 – 45 ^oC
• Relative humidity range from 0 to 85% for 45 – 70 ^oC
• Relative humidity resolution ± 0.1%
• Relative humidity stability ± 0.1% over 6 hours
• RH range accuracy from 10 – 45 ^oC ± 0.5%3
• RH range accuracy from 45 – 70 ^oC ± 1%3

Organic Vapor Generation and Measurement using Speed of Sound Sensor

• Partial pressure range from 0 to 90% P/P_o
• P/Po resolution ± 0.1%
• P/Po accuracy from 10 – 70 oC ±1% P/P_o

Mass Measurement

Ultrabalance Low Mass

• Maximum load: 1000 mg
• Mass change: ±150 mg
• Resolution: 0.01 μg
• Balance noise: ≤ 0.3 μg

Ultrabalance High Mass

• Maximum load: 5000 mg
• Mass change: ±1000 mg
• Resolution: 0.1 μg
• Balance noise: ≤ 3 μg

System Information

Dimensions:     520 mm (W) x 980 mm (H) x 610 mm (D)

20.4″ (W) x 38.58″ (H) x 24.01″ (D)

Weight:              80 kg (180 lb)

Electrical:         200-240 V, 50/60 Hz, 1500 VA

Hardware Configuration

• AQUA: 1 humidity sensor
• Organic: 1 humidity sensor plus 1 SoS sensor, (1 reservoir)

System Software

DVS Control Software:

• Sample pre-heating
• Vapor sorption
• Temperature changes in a single experiment
• Ramp or step changes in relative humidity
• Automated video image and IR/Raman spectra acquisition
• Complex isotherm experiments
• Organic vapor sorption partial pressure
• Experimental stages may be based on fixed-time or user-defined dm/dt criteria
• Experiments may include half, full or multiple partial pressure or temperature cycles
• WindowsTM 10

DVS Analysis Software:

• Isotherms
• Permeability and diffusion
• Kinetics information
• Surface area models
• Amorphous content
• Heat of sorption
• Tg determinations

Software Options:

Standard

• Control Software
• Standard Analysis

Advanced

• Advanced Analysis Suite
• Isotherm Analysis Suite

21CFR Part 11 software solution (optional)